y 16 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3553	Y16		Rho , Ras
	Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated signaling functions.		Rho , Ras
TQ0003L1	740 Y-P acetate	PDGFR 740Y-P Acetate,740YPDGFR acetate,740 Y-P acetate(1236188-16-1 Free base)	PI3K
	740 Y-P acetate (740YPDGFR acetate) is a potent and cell-permeable PI3K activator.740 Y-P acetate tends to bind to GST fusion proteins containing the N- and C-terminal SH2 structural domains of p85, but not to GST alone.		PI3K
TQ0003L	740 Y-P(TFA)(1236188-16-1 free base)	PDGFR 740Y-P(TFA),740 Y-P(TFA),740YPDGFR(TFA)	PI3K
	740 Y-P(TFA)(1236188-16-1 free base) (740YPDGFR(TFA)) is a potent and cell-permeable activator of PI3K.		PI3K
TP1380	Galanin (1-16), mouse, porcine, rat		Neuropeptide Y Receptor
	Galanin (1-16), mouse, porcine, rat is a hippocampal galanin receptor agonist(Kd = 3 nM) with high biological activity on locus coeruleus neurons.		Neuropeptide Y Receptor
TP2327L	Y16 acetate(429653-73-6 free base)	Y16 acetate(53-73-6 free base),ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE acetate	Rho
	Y16 acetate(429653-73-6 free base) is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated signaling functions.		Rho
T3710	XMD16-5		Tyrosinase , PPAR
	XMD16-5 is a TNK2 inhibitor. TNK2 genomic amplification has been associated with late-stage or metastatic lung and prostate Ys. Overexpression of TNK2 promoted metastasis in a mouse model of breast Y. TNK2 signaling is d...		Tyrosinase , PPAR
T36141	Boscalid		Mitochondrial Metabolism
	Boscalid is a broad-spectrum carboxamide fungicide that inhibits fungal respiration by binding to the ubiquinone site of mitochondrial complex II/succinate dehydrogenase.1It suppresses mycelial growth ofS. minorby 87 to ...		Mitochondrial Metabolism
T36723	Desmethyl Ranolazine
	Desmethyl ranolazine is a metabolite of the antianginal agent ranolazine .1It is formed from ranolazine by the cytochrome P450 (CYP) isoform CYP3A. 1.Wang, Y., Chen, X., Sun, Z., et al.Development and validation of a sen...
T35435	β-D-Ribofuranose 1,2,3,5-tetraacetate
	β-D-Ribofuranose 1,2,3,4-tetraacetate is a precursor in the synthesis of nucleosides with antiproliferative activity against cancer cells.1,2 1.Furukawa, Y., and Honjo, M.A novel method for the synthesis of purine nucleo...
T37065	6-Chloro-2-fluoropurine
	6-Chloro-2-fluoropurine is a heterocyclic building block.1,2It has been used in the synthesis of purine nucleosides that inhibit cyclin-dependent kinases (CDKs)in vitro.16-Chloro-2-fluoropurine has also been used in the ...
T36639	Donecopride (fumarate hydrate)
	Donecopride is a partial agonist of the serotonin (5-HT) receptor subtype 5-HT4E(Ki= 8.5 nM) and an inhibitor of acetylcholinesterase (AChE; IC50= 16 nM).1It is selective for AChE over butyrylcholinesterase (BChE; IC50= ...
T35791	Palmitic acid-13C
	Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid i...
T35790	Palmitic acid-1,2,3,4-13C4	Palmitic Acid-13C (C1, C2, C3, and C4 labeled)
	Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20%...
T37452	Stephacidin B
	Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, includ...
T36679	Rp-cAMPS sodium salt
	Rp-cAMPS sodium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 μM and 4.5 μM, respectively) antagonist. Rp-cAMPS sodium salt is resistant to hydrolysis b...
T37847	Zonisamide-13C2,15N	Zonisamide-13C2,15N
	Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels ...